Linker Information
General Information of This Linker
| Linker ID |
LIN0DZDGX
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|---|---|---|---|---|---|---|
| Linker Name |
US11141490B2-Tras-1-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C4H6N2O2
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| Isosmiles |
O=C(N1N)CCC1=O
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| InChI |
InChI=1S/C4H6N2O2/c5-6-3(7)1-2-4(6)8/h1-2,5H2
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| InChIKey |
FLTYUHLOJTZHAP-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
114.104
|
Polar area
|
63.4
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Complexity
|
114.9737366
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xlogp Value
|
-0.9909
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Heavy Count
|
8
|
Rot Bonds
|
0
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Hbond acc
|
3
|
Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker