Linker Information
General Information of This Linker
| Linker ID |
LIN0DZCAR
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| Linker Name |
P5 (PEG2)-VA-PAB linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H39N4O10PS
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| Isosmiles |
CC([C@H](NC(C1=CC=C(NP(/C=C\S)(OCCOCCO)=O)C=C1)=O)C(N[C@@H](C)C(NC2=CC=C(COC(O)=O)C=C2)=O)=O)C
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| InChI |
InChI=1S/C29H39N4O10PS/c1-19(2)25(28(37)30-20(3)26(35)31-23-8-4-21(5-9-23)18-42-29(38)39)32-27(36)22-6-10-24(11-7-22)33-44(40,16-17-45)43-15-14-41-13-12-34/h4-11,16-17,19-20,25,34,45H,12-15,18H2,1-3H3,(H,30,37)(H,31,35)(H,32,36)(H,33,40)(H,38,39)/b17-16-/t20-,25-,44?/m0/s1
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| InChIKey |
NYTLBVVDJCXBBP-BAIGCBTLSA-N
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| Pharmaceutical Properties |
Molecule Weight
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666.69
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Polar area
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201.62
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Complexity
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1290.811944
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xlogp Value
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3.8105
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Heavy Count
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45
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Rot Bonds
|
18
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Hbond acc
|
10
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker