Linker Information
General Information of This Linker
| Linker ID |
LIN0DYZDF
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| Linker Name |
(S)-75-oxo-76- (4- (3-tosyl-2- (tosylmethyl)propanoyl)benzamido) 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxa-74 azanonaheptacontan-79-oic acid
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C79H130N2O33S2
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC([C@@H](NC(C1=CC=C(C(C(CS(=O)(C2=CC=C(C)C=C2)=O)CS(=O)(C3=CC=C(C)C=C3)=O)=O)C=C1)=O)CCC(O)=O)=O
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| InChI |
InChI=1S/C79H130N2O33S2/c1-68-4-12-73(13-5-68)115(87,88)66-72(67-116(89,90)74-14-6-69(2)7-15-74)77(84)70-8-10-71(11-9-70)78(85)81-75(16-17-76(82)83)79(86)80-18-19-92-22-23-94-26-27-96-30-31-98-34-35-100-38-39-102-42-43-104-46-47-106-50-51-108-54-55-110-58-59-112-62-63-114-65-64-113-61-60-111-57-56-109-53-52-107-49-48-105-45-44-103-41-40-101-37-36-99-33-32-97-29-28-95-25-24-93-21-20-91-3/h4-15,72,75H,16-67H2,1-3H3,(H,80,86)(H,81,85)(H,82,83)/t75-/m0/s1
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| InChIKey |
RRKBNVVCZPAHIP-AREVDUJESA-N
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| Pharmaceutical Properties |
Molecule Weight
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1700.024
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Polar area
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402.37
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Complexity
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2871.071057
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xlogp Value
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3.15774
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Heavy Count
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116
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Rot Bonds
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86
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Hbond acc
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32
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Hbond Donor
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3
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Each Antibody-drug Conjugate Related to This Linker