Linker Information
General Information of This Linker
| Linker ID |
LIN0DYKJL
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| Linker Name |
Geranyl ketone pyrophosphate oxime ligation
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| Linker Type |
CaaX-motif based site-specific conjugation linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H52N2O12S
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| Isosmiles |
CSC/C=C(\C)CC/C=C(\C)CC/C(C)=N/OCCOCCOCCNC(=O)c1cc(CO)ccc1OC1OC(C(=O)O)C(O)C(O)C1O
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| InChI |
InChI=1S/C34H52N2O12S/c1-22(6-5-7-23(2)12-19-49-4)8-9-24(3)36-46-18-17-45-16-15-44-14-13-35-32(41)26-20-25(21-37)10-11-27(26)47-34-30(40)28(38)29(39)31(48-34)33(42)43/h6,10-12,20,28-31,34,37-40H,5,7-9,13-19,21H2,1-4H3,(H,35,41)(H,42,43)/b22-6+,23-12+,36-24+
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| InChIKey |
WTEPMOWYUFGBCI-XWZVYFMSSA-N
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| Pharmaceutical Properties |
Molecule Weight
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712.859
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Polar area
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205.83
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Complexity
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712.3240961
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xlogp Value
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2.4214
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Heavy Count
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49
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Rot Bonds
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23
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Hbond acc
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13
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Hbond Donor
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6
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Each Antibody-drug Conjugate Related to This Linker