Linker Information
General Information of This Linker
| Linker ID |
LIN0DYDTQ
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| Linker Name |
IG-L-76 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C59H81FN14O21
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| Isosmiles |
CN(CC(N(CC(N(C)CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(O)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)=O)C)=O)C(CCCOC1=C(F)C(N2C(CCC2=O)=O)=CC=C1CCC(N[C@@H](CC(N)=O)C(NC3=CC=C(C=C3)COC(O)=O)=O)=O)=O
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| InChI |
InChI=1S/C59H81FN14O21/c1-64(43(77)12-11-23-94-57-37(15-19-40(56(57)60)74-44(78)21-22-45(74)79)16-20-42(76)63-39(24-41(61)75)58(91)62-38-17-13-36(14-18-38)35-95-59(92)93)25-46(80)65(2)26-47(81)66(3)27-48(82)67(4)28-49(83)68(5)29-50(84)69(6)30-51(85)70(7)31-52(86)71(8)32-53(87)72(9)33-54(88)73(10)34-55(89)90/h13-15,17-19,39H,11-12,16,20-35H2,1-10H3,(H2,61,75)(H,62,91)(H,63,76)(H,89,90)(H,92,93)/t39-/m0/s1
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| InChIKey |
JJNKPXQGEHXDJG-KDXMTYKHSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1341.372
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Polar area
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434.83
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Complexity
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3112.142143
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xlogp Value
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-3.5672
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Heavy Count
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95
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Rot Bonds
|
36
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Hbond acc
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19
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker