Linker Information
General Information of This Linker
| Linker ID |
LIN0DXWGI
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| Linker Name |
CN113549127A-ADC-6-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C44H77N9O17S
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| Isosmiles |
OC([C@@H](NC([C@H](NC(OCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCNC(C1=CN=C(SCCC)N=C1)=O)=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C44H77N9O17S/c1-4-29-71-43-50-30-34(31-51-43)39(56)48-9-6-8-36(54)46-11-13-62-15-17-64-19-21-66-23-25-68-27-28-69-26-24-67-22-20-65-18-16-63-14-12-47-37(55)32-70-44(61)53-38(33(2)3)40(57)52-35(41(58)59)7-5-10-49-42(45)60/h30-31,33,35,38H,4-29,32H2,1-3H3,(H,46,54)(H,47,55)(H,48,56)(H,52,57)(H,53,61)(H,58,59)(H3,45,49,60)/t35-,38+/m0/s1
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| InChIKey |
BVIXIPPSCHMKLU-ZGAWMTGXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1036.213
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Polar area
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346.77
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Complexity
|
1523.532103
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xlogp Value
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-0.3774
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Heavy Count
|
71
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Rot Bonds
|
46
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Hbond acc
|
19
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker