Linker Information
General Information of This Linker
| Linker ID |
LIN0DVMYV
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| Linker Name |
CN119630431A-ADC-66-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C66H96N6O22S2
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| Isosmiles |
O=C(N1CCOCCC(N[C@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)=O)=O)C(SC3=CC=CC=C3)=C(SC4=CC=CC=C4)C1=O
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| InChI |
InChI=1S/C66H96N6O22S2/c1-82-27-28-85-31-32-87-35-36-89-39-40-91-43-44-93-47-48-94-46-45-92-42-41-90-38-37-88-34-33-86-30-29-84-24-20-57(73)67-22-12-11-19-55(63(78)68-50-59(75)71-56(64(79)69-51-60(76)77)49-52-13-5-2-6-14-52)70-58(74)21-25-83-26-23-72-65(80)61(95-53-15-7-3-8-16-53)62(66(72)81)96-54-17-9-4-10-18-54/h2-10,13-18,55-56H,11-12,19-51H2,1H3,(H,67,73)(H,68,78)(H,69,79)(H,70,74)(H,71,75)(H,76,77)/t55-,56+/m1/s1
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| InChIKey |
LUIJXIPYILYVIL-PLVVXOMOSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1389.648
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Polar area
|
340.17
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Complexity
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2494.324685
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xlogp Value
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2.593
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Heavy Count
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96
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Rot Bonds
|
61
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Hbond acc
|
23
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker