Linker Information
General Information of This Linker
| Linker ID |
LIN0DTTQK
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| Linker Name |
CN112341521B+Linker22
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C31H42N8O10S
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| Isosmiles |
CC([C@H](NC(CCCCN(CC1=C2C=NC(S(C)(=O)=O)=N1)C2=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC3=CC=C(C=C3)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C31H42N8O10S/c1-18(2)25(38-24(40)8-4-5-14-39-16-23-21(28(39)43)15-34-30(37-23)50(3,47)48)27(42)36-22(7-6-13-33-29(32)44)26(41)35-20-11-9-19(10-12-20)17-49-31(45)46/h9-12,15,18,22,25H,4-8,13-14,16-17H2,1-3H3,(H,35,41)(H,36,42)(H,38,40)(H,45,46)(H3,32,33,44)/t22-,25-/m0/s1
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| InChIKey |
BFGBIUCBXQEKMO-DHLKQENFSA-N
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| Pharmaceutical Properties |
Molecule Weight
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718.79
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Polar area
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269.18
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Complexity
|
1613.001962
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xlogp Value
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0.9136
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Heavy Count
|
50
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Rot Bonds
|
18
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Hbond acc
|
11
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker