Linker Information
General Information of This Linker
| Linker ID |
LIN0DTRNB
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Linker of ADC2-56
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C24H28N6O9
|
|||||
| Isosmiles |
O=C(N1CC(NCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)=O)=O)=O)C=CC1=O
|
|||||
| InChI |
InChI=1S/C24H28N6O9/c31-17(8-9-25-20(34)14-30-21(35)6-7-22(30)36)26-11-18(32)27-12-19(33)29-16(24(39)28-13-23(37)38)10-15-4-2-1-3-5-15/h1-7,16H,8-14H2,(H,25,34)(H,26,31)(H,27,32)(H,28,39)(H,29,33)(H,37,38)/t16-/m0/s1
|
|||||
| InChIKey |
CSGFKOHZDUKCDY-INIZCTEOSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
544.521
|
Polar area
|
220.18
|
||
|
Complexity
|
1081.952245
|
xlogp Value
|
-3.4216
|
|||
|
Heavy Count
|
39
|
Rot Bonds
|
15
|
|||
|
Hbond acc
|
8
|
Hbond Donor
|
6
|
|||
Each Antibody-drug Conjugate Related to This Linker