Linker Information
General Information of This Linker
| Linker ID |
LIN0DTOIM
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|---|---|---|---|---|---|---|
| Linker Name |
CN113549127A-ADC-10-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C41H70N6O13S
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| Isosmiles |
NCCCC[C@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC#CC1=CN=C(SCCC)N=C1)=O)=O)=O)C=O
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| InChI |
InChI=1S/C41H70N6O13S/c1-2-30-61-41-45-31-36(32-46-41)8-4-3-5-10-38(49)43-12-14-52-16-18-54-20-22-56-24-26-58-28-29-59-27-25-57-23-21-55-19-17-53-15-13-44-39(50)34-60-35-40(51)47-37(33-48)9-6-7-11-42/h31-33,37H,2-3,5-7,9-30,34-35,42H2,1H3,(H,43,49)(H,44,50)(H,47,51)/t37-/m0/s1
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| InChIKey |
LBZRQKINZWBJAP-QNGWXLTQSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
887.107
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Polar area
|
239.24
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Complexity
|
1214.728127
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xlogp Value
|
0.695
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Heavy Count
|
61
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Rot Bonds
|
43
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Hbond acc
|
17
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker