Linker Information
General Information of This Linker
| Linker ID |
LIN0DRYEV
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Hydrophilic linker of XMT-2056
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C65H112N12O35
|
|||||
| Isosmiles |
C[C@H](NC(=O)CCOCCOCCNC(=O)CC[C@H](NC(=O)CN1C(=O)C=CC1=O)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)N[C@@H](CCC(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C(=O)O
|
|||||
| InChI |
InChI=1S/C65H112N12O35/c1-41(65(101)102)74-50(86)8-12-103-16-18-105-14-10-66-48(84)4-2-43(76-56(92)38-77-57(93)6-7-58(77)94)64(100)73-37-55(91)71-36-54(90)70-35-53(89)69-34-52(88)67-11-15-106-19-21-108-23-25-110-27-29-112-31-30-111-28-26-109-24-22-107-20-17-104-13-9-51(87)75-42(63(99)72-33-45(81)60(96)62(98)47(83)40-79)3-5-49(85)68-32-44(80)59(95)61(97)46(82)39-78/h6-7,41-47,59-62,78-83,95-98H,2-5,8-40H2,1H3,(H,66,84)(H,67,88)(H,68,85)(H,69,89)(H,70,90)(H,71,91)(H,72,99)(H,73,100)(H,74,86)(H,75,87)(H,76,92)(H,101,102)/t41-,42-,43-,44-,45-,46+,47+,59+,60+,61+,62+/m0/s1
|
|||||
| InChIKey |
KWWOMQCVHJOVFM-MKOXISCLSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
1621.66
|
Polar area
|
689.38
|
||
|
Complexity
|
1620.735303
|
xlogp Value
|
-14.2217
|
|||
|
Heavy Count
|
112
|
Rot Bonds
|
70
|
|||
|
Hbond acc
|
34
|
Hbond Donor
|
22
|
|||
Each Antibody-drug Conjugate Related to This Linker