Linker Information
General Information of This Linker
| Linker ID |
LIN0DQCFP
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| Linker Name |
Daratumumab-I-36-5.03 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C53H83FN14O15
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| Isosmiles |
CC(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@H](C(NCCOCCNC(C1=CC=C(OC(CCOCCOCCOCCOCCOCCOCCN)=O)C(F)=C1)=O)=O)CC2=CNC3=C2C=CC=C3)=O)=O)CCCNC(N)=N)=O)=O
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| InChI |
InChI=1S/C53H83FN14O15/c1-36(69)66-43(9-5-15-63-53(58)59)51(75)68-42(8-4-14-62-52(56)57)49(73)65-35-46(70)67-44(33-38-34-64-41-7-3-2-6-39(38)41)50(74)61-17-21-78-20-16-60-48(72)37-10-11-45(40(54)32-37)83-47(71)12-18-76-22-24-79-26-28-81-30-31-82-29-27-80-25-23-77-19-13-55/h2-3,6-7,10-11,32,34,42-44,64H,4-5,8-9,12-31,33,35,55H2,1H3,(H,60,72)(H,61,74)(H,65,73)(H,66,69)(H,67,70)(H,68,75)(H4,56,57,62)(H4,58,59,63)/t42-,43-,44-/m0/s1
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| InChIKey |
PDQBAFJIVMXLNN-KJFLPAQCSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1175.328
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Polar area
|
431.12
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Complexity
|
2359.561149
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xlogp Value
|
-2.11686
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Heavy Count
|
83
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Rot Bonds
|
46
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Hbond acc
|
18
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Hbond Donor
|
14
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Each Antibody-drug Conjugate Related to This Linker