Linker Information
General Information of This Linker
| Linker ID |
LIN0DNSNO
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|---|---|---|---|---|---|---|
| Linker Name |
DBCO-PEG8-glu
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C52H67N3O21
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| Isosmiles |
O=C(CCC(N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3)=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(NC4=CC(COC(O)=O)=CC=C4O[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)=O
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| InChI |
InChI=1S/C52H67N3O21/c56-43(13-14-45(58)55-34-39-7-2-1-5-37(39)10-11-38-6-3-4-8-41(38)55)53-16-18-67-20-22-69-24-26-71-28-30-73-32-31-72-29-27-70-25-23-68-21-19-66-17-15-44(57)54-40-33-36(35-74-52(64)65)9-12-42(40)75-51-48(61)46(59)47(60)49(76-51)50(62)63/h1-9,12,33,46-49,51,59-61H,13-32,34-35H2,(H,53,56)(H,54,57)(H,62,63)(H,64,65)/t46-,47-,48+,49-,51+/m0/s1
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| InChIKey |
GLVPDHJTSQYXME-BLHAFVGPSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1070.108
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Polar area
|
315.33
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Complexity
|
2263.020531
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xlogp Value
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1.4566
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Heavy Count
|
76
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Rot Bonds
|
36
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Hbond acc
|
19
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker