Linker Information
General Information of This Linker
| Linker ID |
LIN0DIGYN
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|---|---|---|---|---|---|---|
| Linker Name |
Mal-glucuronide-PABC
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C22H25N3O12
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| Isosmiles |
O=C(CCN1C(=O)C=CC1=O)NCC(=O)Nc1cc(CO)ccc1O[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@@H]1O
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| InChI |
InChI=1S/C22H25N3O12/c26-9-10-1-2-12(36-22-19(33)17(31)18(32)20(37-22)21(34)35)11(7-10)24-14(28)8-23-13(27)5-6-25-15(29)3-4-16(25)30/h1-4,7,17-20,22,26,31-33H,5-6,8-9H2,(H,23,27)(H,24,28)(H,34,35)/t17-,18-,19-,20-,22+/m0/s1
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| InChIKey |
KMRPRJZQBMVJMT-SPNOPHAYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
523.451
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Polar area
|
232.26
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Complexity
|
523.1438232
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xlogp Value
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-3.1803
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Heavy Count
|
37
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Rot Bonds
|
10
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker