Linker Information
General Information of This Linker
| Linker ID |
LIN0DGVVW
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| Linker Name |
CN112604004B-SCT-200-C-4-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H44N6O10
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| Isosmiles |
O=C(OCC1=CC=C(C=C1)NC(CNC(C(C2=CC=CC=C2)CNC(CNC(CNC(CC3CCC(CCN4C(C=CC4=O)=O)CC3)=O)=O)=O)=O)=O)O
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| InChI |
InChI=1S/C37H44N6O10/c44-30(18-25-8-6-24(7-9-25)16-17-43-34(48)14-15-35(43)49)39-20-32(46)40-21-31(45)38-19-29(27-4-2-1-3-5-27)36(50)41-22-33(47)42-28-12-10-26(11-13-28)23-53-37(51)52/h1-5,10-15,24-25,29H,6-9,16-23H2,(H,38,45)(H,39,44)(H,40,46)(H,41,50)(H,42,47)(H,51,52)
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| InChIKey |
IRIIEIOUIOCAFU-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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732.791
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Polar area
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229.41
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Complexity
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1592.261737
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xlogp Value
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1.5799
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Heavy Count
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53
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Rot Bonds
|
18
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker