Linker Information
General Information of This Linker
| Linker ID |
LIN0DGADV
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| Linker Name |
CN112341521B+Linker31
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H36N6O9S
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| Isosmiles |
CC([C@H](NC(CCCCN1CC2=C(C=NC(S(C)(=O)=O)=N2)C1=O)=O)C(N[C@@H](C)C(NC3=CC=C(C=C3)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C28H36N6O9S/c1-16(2)23(25(37)30-17(3)24(36)31-19-10-8-18(9-11-19)15-43-28(39)40)33-22(35)7-5-6-12-34-14-21-20(26(34)38)13-29-27(32-21)44(4,41)42/h8-11,13,16-17,23H,5-7,12,14-15H2,1-4H3,(H,30,37)(H,31,36)(H,33,35)(H,39,40)/t17-,23-/m0/s1
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| InChIKey |
XGIJPMFCHDPNNB-SBUREZEXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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632.696
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Polar area
|
214.06
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Complexity
|
1450.381763
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xlogp Value
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1.485
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Heavy Count
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44
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Rot Bonds
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14
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Hbond acc
|
10
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Hbond Donor
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4
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Each Antibody-drug Conjugate Related to This Linker