Linker Information
General Information of This Linker
| Linker ID |
LIN0DFXJR
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| Linker Name |
TWI857167B-IC-105-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H46F4O15
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| Isosmiles |
O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC1=C(F)C(F)=C(O)C(F)=C1F)=O
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| InChI |
InChI=1S/C30H46F4O15/c31-25-27(33)30(28(34)26(32)29(25)38)49-24(37)2-4-40-6-8-42-10-12-44-14-16-46-18-20-48-22-21-47-19-17-45-15-13-43-11-9-41-7-5-39-3-1-23(35)36/h38H,1-22H2,(H,35,36)
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| InChIKey |
GVABOZKNUWSZCO-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
722.675
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Polar area
|
176.13
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Complexity
|
931.7357847
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xlogp Value
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1.8848
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Heavy Count
|
49
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Rot Bonds
|
34
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Hbond acc
|
14
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker