Linker Information
General Information of This Linker
| Linker ID |
LIN0DFJGH
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| Linker Name |
Mal-PEG8-Val-Cit-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C44H71N7O16
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| Isosmiles |
CC([C@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C=C2)CO)=O)=O)C
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| PubChem CID | ||||||
| InChI |
InChI=1S/C44H71N7O16/c1-33(2)41(43(58)49-36(4-3-13-47-44(45)59)42(57)48-35-7-5-34(32-52)6-8-35)50-38(54)12-16-60-18-20-62-22-24-64-26-28-66-30-31-67-29-27-65-25-23-63-21-19-61-17-14-46-37(53)11-15-51-39(55)9-10-40(51)56/h5-10,33,36,41,52H,3-4,11-32H2,1-2H3,(H,46,53)(H,48,57)(H,49,58)(H,50,54)(H3,45,47,59)/t36-,41-/m0/s1
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| InChIKey |
CVOMRLRMAHHQSI-ASVWIKLXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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954.085
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Polar area
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302.97
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Complexity
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1534.771927
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xlogp Value
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-0.8543
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Heavy Count
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67
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Rot Bonds
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41
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Hbond acc
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16
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Hbond Donor
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7
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Each Antibody-drug Conjugate Related to This Linker