Linker Information
General Information of This Linker
| Linker ID |
LIN0DDIEH
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| Linker Name |
CN114269749B anti-FolR1 ADC1 Linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C48H63N7O11
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| Isosmiles |
CC(C)[C@H](NC(CCOCCOCCOCCOCCNC(CCC(N(C(C=CC=C1)=C1C#C2)CC3=C2C=CC=C3)=O)=O)=O)C(N[C@H](C(NC4=CC=C(CO)C=C4)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C48H63N7O11/c1-34(2)45(47(61)53-40(11-7-22-51-48(49)62)46(60)52-39-17-13-35(33-56)14-18-39)54-43(58)21-24-63-26-28-65-30-31-66-29-27-64-25-23-50-42(57)19-20-44(59)55-32-38-10-4-3-8-36(38)15-16-37-9-5-6-12-41(37)55/h3-6,8-10,12-14,17-18,34,40,45,56H,7,11,19-33H2,1-2H3,(H,50,57)(H,52,60)(H,53,61)(H,54,58)(H3,49,51,62)/t40-,45-/m0/s1
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| InChIKey |
ZGKLBSKUAQTERI-FQDNZFBXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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914.07
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Polar area
|
248.98
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Complexity
|
2032.450432
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xlogp Value
|
2.491
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Heavy Count
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66
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Rot Bonds
|
29
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker