Linker Information
General Information of This Linker
| Linker ID |
LIN0CYVAU
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| Linker Name |
Valine-alanine (cleavable linker)
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H50N4O17S
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| Isosmiles |
CC(C)[C@@H](NC(=O)CN1C(=O)[C@H](N2C(=O)C=CC2=O)C[C@@H]1COCCS(=O)(=O)O)C(=O)C[C@@H](C)C(=O)Nc1ccc(CO)c(CCC2OC(C(=O)O)[C@@H](O)C(O)[C@H]2O)c1
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| InChI |
InChI=1S/C37H50N4O17S/c1-18(2)30(39-27(44)15-40-23(17-57-10-11-59(54,55)56)14-24(36(40)51)41-28(45)8-9-29(41)46)25(43)12-19(3)35(50)38-22-6-4-21(16-42)20(13-22)5-7-26-31(47)32(48)33(49)34(58-26)37(52)53/h4,6,8-9,13,18-19,23-24,26,30-34,42,47-49H,5,7,10-12,14-17H2,1-3H3,(H,38,50)(H,39,44)(H,52,53)(H,54,55,56)/t19-,23-,24-,26?,30-,31+,32?,33+,34?/m1/s1
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| InChIKey |
YFYZLTKHZRCMNG-XYFLPFCVSA-N
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| Pharmaceutical Properties |
Molecule Weight
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854.885
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Polar area
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324.01
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Complexity
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854.2891671
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xlogp Value
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-2.4803
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Heavy Count
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59
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Rot Bonds
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20
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Hbond acc
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15
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Hbond Donor
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8
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Each Antibody-drug Conjugate Related to This Linker