Linker Information
General Information of This Linker
| Linker ID |
LIN0CWWOI
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| Linker Name |
EP4494658A1 antibody-drug conjugate 1
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H40N6O7
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@H](C(NC2=CC=C(C=C2)CO)=O)CCCNC(N)=O)=O)C
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| InChI |
InChI=1S/C28H40N6O7/c1-18(2)25(33-22(36)8-4-3-5-16-34-23(37)13-14-24(34)38)27(40)32-21(7-6-15-30-28(29)41)26(39)31-20-11-9-19(17-35)10-12-20/h9-14,18,21,25,35H,3-8,15-17H2,1-2H3,(H,31,39)(H,32,40)(H,33,36)(H3,29,30,41)/t21-,25-/m0/s1
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| InChIKey |
AMKBTTRWLGVRER-OFVILXPXSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
572.663
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Polar area
|
200.03
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Complexity
|
1051.539999
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xlogp Value
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0.6769
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Heavy Count
|
41
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Rot Bonds
|
17
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Hbond acc
|
7
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker