Linker Information
General Information of This Linker
| Linker ID |
LIN0CNZMJ
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| Linker Name |
P5 (PEG24)- VC-PAB linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C76H133N6O33PS
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| Isosmiles |
CC(C(NC(C1=CC=C(NP(/C=C\S)(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)=O)C=C1)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(O)=O)C=C2)=O)=O)C
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| InChI |
InChI=1S/C76H133N6O33PS/c1-65(2)71(74(86)80-70(4-3-13-78-75(77)87)73(85)79-68-9-5-66(6-10-68)64-114-76(88)89)81-72(84)67-7-11-69(12-8-67)82-116(90,62-63-117)115-61-60-113-59-58-112-57-56-111-55-54-110-53-52-109-51-50-108-49-48-107-47-46-106-45-44-105-43-42-104-41-40-103-39-38-102-37-36-101-35-34-100-33-32-99-31-30-98-29-28-97-27-26-96-25-24-95-23-22-94-21-20-93-19-18-92-17-16-91-15-14-83/h5-12,62-63,65,70-71,83,117H,3-4,13-61,64H2,1-2H3,(H,79,85)(H,80,86)(H,81,84)(H,82,90)(H,88,89)(H3,77,78,87)/b63-62-/t70-,71?,116?/m0/s1
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| InChIKey |
XVMJOSGAPVVRKC-XDKUPDTGSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1721.95
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Polar area
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459.8
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Complexity
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2589.394716
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xlogp Value
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3.6043
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Heavy Count
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117
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Rot Bonds
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88
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Hbond acc
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33
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker