Linker Information
General Information of This Linker
| Linker ID |
LIN0CMUPH
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| Linker Name |
CN113549127A-ADC-21-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C39H64N8O13S
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| Isosmiles |
SC1=NC=C(C#CCCCC(N=N2)=CN2CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@H](C(O)=O)CCCCN)=O)=O)C=N1
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| InChI |
InChI=1S/C39H64N8O13S/c40-9-5-4-8-35(38(50)51)44-37(49)32-60-31-36(48)41-10-12-52-14-16-54-18-20-56-22-24-58-26-27-59-25-23-57-21-19-55-17-15-53-13-11-47-30-34(45-46-47)7-3-1-2-6-33-28-42-39(61)43-29-33/h28-30,35H,1,3-5,7-27,31-32,40H2,(H,41,48)(H,44,49)(H,50,51)(H,42,43,61)/t35-/m0/s1
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| InChIKey |
YMYIJJCUBAIQHB-DHUJRADRSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
885.051
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Polar area
|
261.08
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Complexity
|
1399.758843
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xlogp Value
|
-0.3048
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Heavy Count
|
61
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Rot Bonds
|
40
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Hbond acc
|
19
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker