Linker Information
General Information of This Linker
| Linker ID |
LIN0CIZGD
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| Linker Name |
MC-Val-Ala-RG-8
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C63H100N6O22
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| Isosmiles |
O=C(N[C@@H](C)C(NC1=CC=C(COC(NCC2=CC=C(CCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)C=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C63H100N6O22/c1-49(2)59(67-56(70)11-7-6-8-20-69-57(71)18-19-58(69)72)61(74)65-50(3)60(73)66-54-16-13-52(14-17-54)48-91-62(75)64-47-53-15-12-51(46-55(53)68(4)63(76)77)10-9-21-79-24-25-81-28-29-83-32-33-85-36-37-87-40-41-89-44-45-90-43-42-88-39-38-86-35-34-84-31-30-82-27-26-80-23-22-78-5/h12-19,46,49-50,59H,6-11,20-45,47-48H2,1-5H3,(H,64,75)(H,65,74)(H,66,73)(H,67,70)(H,76,77)/t50-,59-/m0/s1
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| InChIKey |
SUPSDVDRARYYMU-LZSNORPBSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1293.513
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Polar area
|
323.54
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Complexity
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2248.539122
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xlogp Value
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4.0748
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Heavy Count
|
91
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Rot Bonds
|
57
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Hbond acc
|
21
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker