General Information of This Linker
Linker ID
LIN0CHTCR
Linker Name
CN119630431A-ADC-3-LINKER
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C26H33N5O10
Isosmiles
O=C(N1CCOCCOCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)=O)=O)C=CC1=O
InChI
InChI=1S/C26H33N5O10/c32-20(8-10-40-12-13-41-11-9-31-23(35)6-7-24(31)36)27-15-21(33)28-16-22(34)30-19(26(39)29-17-25(37)38)14-18-4-2-1-3-5-18/h1-7,19H,8-17H2,(H,27,32)(H,28,33)(H,29,39)(H,30,34)(H,37,38)/t19-/m0/s1
InChIKey
IHUJXXKJHGKDAK-IBGZPJMESA-N
Pharmaceutical Properties
Molecule Weight
575.575
Polar area
209.54
Complexity
1054.294887
xlogp Value
-2.5046
Heavy Count
41
Rot Bonds
19
Hbond acc
9
Hbond Donor
5
Each Antibody-drug Conjugate Related to This Linker