Linker Information
General Information of This Linker
| Linker ID |
LIN0CHTCR
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|---|---|---|---|---|---|---|
| Linker Name |
CN119630431A-ADC-3-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C26H33N5O10
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| Isosmiles |
O=C(N1CCOCCOCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)=O)=O)C=CC1=O
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| InChI |
InChI=1S/C26H33N5O10/c32-20(8-10-40-12-13-41-11-9-31-23(35)6-7-24(31)36)27-15-21(33)28-16-22(34)30-19(26(39)29-17-25(37)38)14-18-4-2-1-3-5-18/h1-7,19H,8-17H2,(H,27,32)(H,28,33)(H,29,39)(H,30,34)(H,37,38)/t19-/m0/s1
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| InChIKey |
IHUJXXKJHGKDAK-IBGZPJMESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
575.575
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Polar area
|
209.54
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Complexity
|
1054.294887
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xlogp Value
|
-2.5046
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Heavy Count
|
41
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Rot Bonds
|
19
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Hbond acc
|
9
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker
