Linker Information
General Information of This Linker
| Linker ID |
LIN0CHRMI
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|---|---|---|---|---|---|---|
| Linker Name |
Linker of ADC3-19
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C17H26N4O8
|
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| Isosmiles |
CC([C@H](NC(CCNC(CNC(/C=C\C(O)=O)=O)=O)=O)C(N[C@@H](C)C(O)=O)=O)C
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| InChI |
InChI=1S/C17H26N4O8/c1-9(2)15(16(27)20-10(3)17(28)29)21-12(23)6-7-18-13(24)8-19-11(22)4-5-14(25)26/h4-5,9-10,15H,6-8H2,1-3H3,(H,18,24)(H,19,22)(H,20,27)(H,21,23)(H,25,26)(H,28,29)/b5-4-/t10-,15-/m0/s1
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| InChIKey |
JTFIIUYUSJJIFI-ACTWMTSASA-N
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| Pharmaceutical Properties |
Molecule Weight
|
414.415
|
Polar area
|
191
|
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Complexity
|
634.9494616
|
xlogp Value
|
-2.0202
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Heavy Count
|
29
|
Rot Bonds
|
12
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Hbond acc
|
6
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker