Linker Information
General Information of This Linker
| Linker ID |
LIN0CFKYQ
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| Linker Name |
CN113549127A-ADC-12-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H51N5O10S
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| Isosmiles |
OC([C@@H](NC(COCC(NCCOCCOCCNC(CCCCCN1C(C(SCCC)CC1=O)=O)=O)=O)=O)CCCCN)=O
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| InChI |
InChI=1S/C29H51N5O10S/c1-2-18-45-23-19-27(38)34(28(23)39)13-7-3-4-9-24(35)31-11-14-42-16-17-43-15-12-32-25(36)20-44-21-26(37)33-22(29(40)41)8-5-6-10-30/h22-23H,2-21,30H2,1H3,(H,31,35)(H,32,36)(H,33,37)(H,40,41)/t22-,23?/m0/s1
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| InChIKey |
WMHSCELCRJAVAR-NQCNTLBGSA-N
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| Pharmaceutical Properties |
Molecule Weight
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661.819
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Polar area
|
215.69
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Complexity
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864.4692002
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xlogp Value
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-0.2019
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Heavy Count
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45
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Rot Bonds
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28
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Hbond acc
|
11
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Hbond Donor
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5
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Each Antibody-drug Conjugate Related to This Linker