Linker Information
General Information of This Linker
| Linker ID |
LIN0CETKX
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| Linker Name |
Linker of ADC3-20
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H55N8O14PS
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| Isosmiles |
O=C(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)[C@@H](NC(CCCCCN2C(C=CC2=O)=O)=O)CCC(NCCOP(OCC[N+](C)(C)C)([O-])=O)=O.[S]
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| InChI |
InChI=1S/C37H55N8O14P.S/c1-45(2,3)19-21-59-60(56,57)58-20-17-38-29(46)14-13-27(42-30(47)12-8-5-9-18-44-33(50)15-16-34(44)51)36(54)40-23-31(48)39-24-32(49)43-28(37(55)41-25-35(52)53)22-26-10-6-4-7-11-26;/h4,6-7,10-11,15-16,27-28H,5,8-9,12-14,17-25H2,1-3H3,(H7-,38,39,40,41,42,43,46,47,48,49,52,53,54,55,56,57);/t27-,28-;/m0./s1
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| InChIKey |
ITCPGRCFUBJBHM-DHBRAOIWSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
898.93
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Polar area
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307.87
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Complexity
|
1651.940454
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xlogp Value
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-2.1303
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Heavy Count
|
61
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Rot Bonds
|
29
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Hbond acc
|
13
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker