Linker Information
General Information of This Linker
| Linker ID |
LIN0CCXTT
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|---|---|---|---|---|---|---|
| Linker Name |
Maleimide-containing OHPAS linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C21H26O10S
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| Isosmiles |
CC1=CC(OS(=O)(OC2=CC=C(CC)C=C2)=O)=C(O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)C=C1
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| InChI |
InChI=1S/C21H26O10S/c1-3-13-5-7-14(8-6-13)30-32(26,27)31-16-10-12(2)4-9-15(16)28-21-20(25)19(24)18(23)17(11-22)29-21/h4-10,17-25H,3,11H2,1-2H3/t17-,18+,19+,20-,21-/m1/s1
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| InChIKey |
OBFDGCUVEXJNPV-XDWAVFMPSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
470.496
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Polar area
|
151.98
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Complexity
|
971.1984215
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xlogp Value
|
0.43872
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Heavy Count
|
32
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Rot Bonds
|
8
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Hbond acc
|
10
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker
