Linker Information
General Information of This Linker
| Linker ID |
LIN0CAAPO
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| Linker Name |
CN113549127A-ADC-8-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C26H42N6O8S
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| Isosmiles |
OC([C@@H](NC(COCC(NCCOCCOCCCN1CC2=C(C=NC(SCCC)=N2)C1=O)=O)=O)CCCCN)=O
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| InChI |
InChI=1S/C26H42N6O8S/c1-2-14-41-26-29-15-19-21(31-26)16-32(24(19)35)9-5-10-38-12-13-39-11-8-28-22(33)17-40-18-23(34)30-20(25(36)37)6-3-4-7-27/h15,20H,2-14,16-18,27H2,1H3,(H,28,33)(H,30,34)(H,36,37)/t20-/m0/s1
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| InChIKey |
KVOXVOCTMJOGCE-FQEVSTJZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
598.723
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Polar area
|
195.3
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Complexity
|
927.3567431
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xlogp Value
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0.189
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Heavy Count
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41
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Rot Bonds
|
23
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Hbond acc
|
11
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker