Linker Information
General Information of This Linker
| Linker ID |
LIN0BYZOL
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| Linker Name |
AsnAlaPABC
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| Linker Type |
Legumain-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H39N7O11
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| Isosmiles |
O=C(NCCOCCOCC(NCC(N[C@@H](CC(N)=O)C(N[C@@H](C)C(NC1=CC=C(C=C1)CO)=O)=O)=O)=O)CCN2C(C=CC2=O)=O
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| InChI |
InChI=1S/C29H39N7O11/c1-18(28(44)34-20-4-2-19(16-37)3-5-20)33-29(45)21(14-22(30)38)35-24(40)15-32-25(41)17-47-13-12-46-11-9-31-23(39)8-10-36-26(42)6-7-27(36)43/h2-7,18,21,37H,8-17H2,1H3,(H2,30,38)(H,31,39)(H,32,41)(H,33,45)(H,34,44)(H,35,40)/t18-,21-/m0/s1
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| InChIKey |
CQBFVNGNOWQEPD-RXVVDRJESA-N
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| Pharmaceutical Properties |
Molecule Weight
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661.669
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Polar area
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264.66
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Complexity
|
1253.539232
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xlogp Value
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-3.437
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Heavy Count
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47
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Rot Bonds
|
21
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker