Linker Information
General Information of This Linker
| Linker ID |
LIN0BXXDQ
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| Linker Name |
D5 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H41N5O9
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| Isosmiles |
CC([C@H](NC(CCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)C(N[C@@H](C)C(NC2=CC=C(CO)C=C2)=O)=O)C
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| InChI |
InChI=1S/C29H41N5O9/c1-19(2)27(29(41)31-20(3)28(40)32-22-6-4-21(18-35)5-7-22)33-24(37)11-14-42-16-17-43-15-12-30-23(36)10-13-34-25(38)8-9-26(34)39/h4-9,19-20,27,35H,10-18H2,1-3H3,(H,30,36)(H,31,41)(H,32,40)(H,33,37)/t20-,27-/m0/s1
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| InChIKey |
MDBYVULYLVHMGQ-DCFHFQCYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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603.673
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Polar area
|
192.47
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Complexity
|
1083.197358
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xlogp Value
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-0.3825
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Heavy Count
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43
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Rot Bonds
|
19
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Hbond acc
|
9
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker