Linker Information
General Information of This Linker
| Linker ID |
LIN0BXLSY
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| Linker Name |
EP4494658A1 antibody-drug conjugate 4
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H50N8O8S
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| Isosmiles |
O=C(N[C@@H](C(C)C)C(NC(CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)CSCCC(N2CN3CN(C(CCCCCC3=O)=O)C2)=O
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| InChI |
InChI=1S/C33H50N8O8S/c1-22(2)30(32(48)37-25(7-6-15-35-33(34)49)31(47)36-24-12-10-23(17-42)11-13-24)38-26(43)18-50-16-14-29(46)41-20-39-19-40(21-41)28(45)9-5-3-4-8-27(39)44/h10-13,22,25,30,42H,3-9,14-21H2,1-2H3,(H,36,47)(H,37,48)(H,38,43)(H3,34,35,49)/t25?,30-/m0/s1
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| InChIKey |
FQRZGKZTUFTHTJ-QNGSWNHHSA-N
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| Pharmaceutical Properties |
Molecule Weight
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718.878
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Polar area
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223.58
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Complexity
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1267.748166
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xlogp Value
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0.6508
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Heavy Count
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50
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Rot Bonds
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16
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Hbond acc
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9
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Hbond Donor
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6
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Each Antibody-drug Conjugate Related to This Linker