Linker Information
General Information of This Linker
| Linker ID |
LIN0BULYB
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| Linker Name |
MP-Gln-Cit-RG-1
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H45N9O11
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| Isosmiles |
O=C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(NCC2=CC=CC=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](CCCC(N)=O)NC(CCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C36H45N9O11/c1-44(36(54)55)27-9-3-2-6-23(27)20-40-35(53)56-21-22-11-13-24(14-12-22)41-32(50)26(8-5-18-39-34(38)52)43-33(51)25(7-4-10-28(37)46)42-29(47)17-19-45-30(48)15-16-31(45)49/h2-3,6,9,11-16,25-26H,4-5,7-8,10,17-21H2,1H3,(H2,37,46)(H,40,53)(H,41,50)(H,42,47)(H,43,51)(H,54,55)(H3,38,39,52)/t25-,26-/m0/s1
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| InChIKey |
IXRZUJLSKVHFIC-UIOOFZCWSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
779.808
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Polar area
|
301.76
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Complexity
|
1726.793609
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xlogp Value
|
0.5545
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Heavy Count
|
56
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Rot Bonds
|
21
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Hbond acc
|
10
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker