General Information of This Linker
Linker ID
LIN0BMSFC
Linker Name
TWI857167B-IC-71-LINKER
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C13H12F4O4
Isosmiles
FC1=C(OC(CCCCCC(O)=O)=O)C(F)=C(F)C=C1F
InChI
InChI=1S/C13H12F4O4/c14-7-6-8(15)12(17)13(11(7)16)21-10(20)5-3-1-2-4-9(18)19/h6H,1-5H2,(H,18,19)
InChIKey
FCPRZFACPGLFBC-UHFFFAOYSA-N
Pharmaceutical Properties
Molecule Weight
308.227
Polar area
63.6
Complexity
491.0801149
xlogp Value
3.1835
Heavy Count
21
Rot Bonds
7
Hbond acc
3
Hbond Donor
1
Each Antibody-drug Conjugate Related to This Linker