Linker Information
General Information of This Linker
| Linker ID |
LIN0BHCLX
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|---|---|---|---|---|---|---|
| Linker Name |
BVP-PEG3-diamine
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| Linker Type |
Flexible dual-reactive (thiol) linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H42N8O11S2
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| Isosmiles |
C=CS(=O)(=O)N1CCN(S(=O)(=O)C=C)C(C(=O)NCc2cn(CCOCCOCCOCC(=O)N(C)CCN(C)C(=O)O)nn2)C1
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| InChI |
InChI=1S/C25H42N8O11S2/c1-5-45(38,39)32-9-10-33(46(40,41)6-2)22(19-32)24(35)26-17-21-18-31(28-27-21)11-12-42-13-14-43-15-16-44-20-23(34)29(3)7-8-30(4)25(36)37/h5-6,18,22H,1-2,7-17,19-20H2,3-4H3,(H,26,35)(H,36,37)
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| InChIKey |
XQNQBAKLDJFAFM-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
694.79
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Polar area
|
223.11
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Complexity
|
46
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xlogp Value
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-2.0549
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Heavy Count
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46
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Rot Bonds
|
21
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Hbond acc
|
13
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker
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