Linker Information
General Information of This Linker
| Linker ID |
LIN0BGNIW
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| Linker Name |
WO2023173026A1-ADC-L078-055-Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H43N7O14
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| Isosmiles |
O=C(N1CCC(NCCOCCOCCOCCOCCC(NCC(NCC(NCC(NCC(NCC(O)=O)=O)=O)=O)=O)=O)=O)C=CC1=O
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| PubChem CID | ||||||
| InChI |
InChI=1S/C28H43N7O14/c36-20(3-6-35-26(42)1-2-27(35)43)29-5-8-47-10-12-49-14-13-48-11-9-46-7-4-21(37)30-15-22(38)31-16-23(39)32-17-24(40)33-18-25(41)34-19-28(44)45/h1-2H,3-19H2,(H,29,36)(H,30,37)(H,31,38)(H,32,39)(H,33,40)(H,34,41)(H,44,45)
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| InChIKey |
QNTGXSMXOZQJCO-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
701.687
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Polar area
|
286.2
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Complexity
|
1094.680551
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xlogp Value
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-5.4602
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Heavy Count
|
49
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Rot Bonds
|
28
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Hbond acc
|
13
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker