Linker Information
General Information of This Linker
| Linker ID |
LIN0BEHDO
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| Linker Name |
IG-L-22 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C61H89N9O21
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| Isosmiles |
C[C@H](NC(CCC1=CC=C(N2C(C=CC2=O)=O)C=C1OCCCC(N(C)CCOCCC(N(C)CCOCCC(N(C)CCOCCC(N(C)CCOCCC(N(C)CCOCCC(O)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](C)C(NC3=CC=C(C=C3)COC(O)=O)=O)=O
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| InChI |
InChI=1S/C61H89N9O21/c1-43(59(81)63-44(2)60(82)64-47-14-10-45(11-15-47)42-91-61(83)84)62-50(71)17-13-46-12-16-48(70-56(77)18-19-57(70)78)41-49(46)90-30-8-9-51(72)65(3)25-36-85-31-20-52(73)66(4)26-37-86-32-21-53(74)67(5)27-38-87-33-22-54(75)68(6)28-39-88-34-23-55(76)69(7)29-40-89-35-24-58(79)80/h10-12,14-16,18-19,41,43-44H,8-9,13,17,20-40,42H2,1-7H3,(H,62,71)(H,63,81)(H,64,82)(H,79,80)(H,83,84)/t43-,44-/m0/s1
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| InChIKey |
BEPGWDYYGTUPDJ-CXNSMIOJSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1284.425
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Polar area
|
365.44
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Complexity
|
2638.461761
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xlogp Value
|
1.4604
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Heavy Count
|
91
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Rot Bonds
|
46
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Hbond acc
|
19
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker