Linker Information
General Information of This Linker
| Linker ID |
LIN0BDPNP
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|---|---|---|---|---|---|---|
| Linker Name |
L101 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C81H144N8O35
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| Isosmiles |
CC(C)[C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@H](C(NC2=CC(CN(C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)C)=C(CO)C=C2)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C81H144N8O35/c1-68(2)77(87-73(91)10-15-100-18-14-89-74(92)8-9-75(89)93)79(97)86-72(5-4-12-83-80(82)98)78(96)85-71-7-6-69(67-90)70(65-71)66-88(3)81(99)84-13-17-102-20-22-104-24-26-106-28-30-108-32-34-110-36-38-112-40-42-114-44-46-116-48-50-118-52-54-120-56-58-122-60-62-124-64-63-123-61-59-121-57-55-119-53-51-117-49-47-115-45-43-113-41-39-111-37-35-109-33-31-107-29-27-105-25-23-103-21-19-101-16-11-76(94)95/h6-9,65,68,72,77,90H,4-5,10-64,66-67H2,1-3H3,(H,84,99)(H,85,96)(H,86,97)(H,87,91)(H,94,95)(H3,82,83,98)/t72-,77-/m0/s1
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| InChIKey |
NNYKFIIPXYWHOH-QZILAHSYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1790.064
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Polar area
|
500.42
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Complexity
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.
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xlogp Value
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-0.4623
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Heavy Count
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124
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Rot Bonds
|
94
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Hbond acc
|
34
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker