Linker Information
General Information of This Linker
| Linker ID |
LIN0AXXKQ
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| Linker Name |
CN119630431A-ADC-47-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H32N4O9S2
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| Isosmiles |
O=C(O)CNC([C@@H](NC(CCOCCOCCN(C1=O)C(C(SC2=CC=CC=C2)=C1SC3=CC=CC=C3)=O)=O)CC(N)=O)=O
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| InChI |
InChI=1S/C29H32N4O9S2/c30-22(34)17-21(27(38)31-18-24(36)37)32-23(35)11-13-41-15-16-42-14-12-33-28(39)25(43-19-7-3-1-4-8-19)26(29(33)40)44-20-9-5-2-6-10-20/h1-10,21H,11-18H2,(H2,30,34)(H,31,38)(H,32,35)(H,36,37)/t21-/m0/s1
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| InChIKey |
QIAJZWZCIYMDAG-NRFANRHFSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
644.728
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Polar area
|
194.43
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Complexity
|
1249.107977
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xlogp Value
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1.1357
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Heavy Count
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44
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Rot Bonds
|
19
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Hbond acc
|
10
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker