Linker Information
General Information of This Linker
| Linker ID |
LIN0AXVIH
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| Linker Name |
CN113549127A-ADC-26-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H62N6O14S2
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| Isosmiles |
NCCCC[C@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN1C(C(N=C(C(CS)=N2)CS)=C2C1)=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C36H62N6O14S2/c37-4-2-1-3-28(36(46)47)40-33(44)25-56-24-32(43)38-5-7-48-9-11-50-13-15-52-17-19-54-21-22-55-20-18-53-16-14-51-12-10-49-8-6-42-23-29-34(35(42)45)41-31(27-58)30(26-57)39-29/h28,57-58H,1-27,37H2,(H,38,43)(H,40,44)(H,46,47)/t28-/m0/s1
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| InChIKey |
IQQMKPWOGMKJPE-NDEPHWFRSA-N
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| Pharmaceutical Properties |
Molecule Weight
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867.054
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Polar area
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250.68
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Complexity
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1224.670208
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xlogp Value
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-0.744
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Heavy Count
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58
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Rot Bonds
|
39
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Hbond acc
|
18
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Hbond Donor
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6
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Each Antibody-drug Conjugate Related to This Linker