Linker Information
General Information of This Linker
| Linker ID |
LIN0AXNQD
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|---|---|---|---|---|---|---|
| Linker Name |
Mc-Val-Cit-PABC-DMAE
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H50N8O8
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| Isosmiles |
CNCCN(C)C(=O)OCc1ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1
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| InChI |
InChI=1S/C33H50N8O8/c1-22(2)29(39-26(42)10-6-5-7-19-41-27(43)15-16-28(41)44)31(46)38-25(9-8-17-36-32(34)47)30(45)37-24-13-11-23(12-14-24)21-49-33(48)40(4)20-18-35-3/h11-16,22,25,29,35H,5-10,17-21H2,1-4H3,(H,37,45)(H,38,46)(H,39,42)(H3,34,36,47)
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| InChIKey |
JNNCESUGQNULLW-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
686.811
|
Polar area
|
221.37
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Complexity
|
49
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xlogp Value
|
0.9724
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Heavy Count
|
49
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Rot Bonds
|
21
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Hbond acc
|
9
|
Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker
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