Linker Information
General Information of This Linker
| Linker ID |
LIN0AWGHM
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|---|---|---|---|---|---|---|
| Linker Name |
Mal-PEG4-Val-Cit-PABC-DMAE
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C40H62N8O13
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| Isosmiles |
CC(C)C(NC(=O)CCOCCOCCOCCOCCC(=O)CCN1C(=O)C=CC1=O)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)N(C)CCN)cc1
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| InChI |
InChI=1S/C40H62N8O13/c1-28(2)36(46-33(50)14-20-58-22-24-60-26-25-59-23-21-57-19-13-31(49)12-17-48-34(51)10-11-35(48)52)38(54)45-32(5-4-16-43-39(42)55)37(53)44-30-8-6-29(7-9-30)27-61-40(56)47(3)18-15-41/h6-11,28,32,36H,4-5,12-27,41H2,1-3H3,(H,44,53)(H,45,54)(H,46,50)(H3,42,43,55)
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| InChIKey |
SCKWZHXHNBVFQH-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
862.979
|
Polar area
|
289.35
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Complexity
|
61
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xlogp Value
|
-0.0429
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Heavy Count
|
61
|
Rot Bonds
|
32
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Hbond acc
|
14
|
Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker
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