Linker Information
General Information of This Linker
| Linker ID |
LIN0AWBIM
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| Linker Name |
Linker of ADC2-41
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H29N5O9S
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| Isosmiles |
O=C(NC1=CC=C(CC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)=O)=O)C=C1)/C=C\C(O)=O.[S]
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| InChI |
InChI=1S/C27H29N5O9.S/c33-21(10-11-25(37)38)31-19-8-6-18(7-9-19)13-22(34)28-14-23(35)29-15-24(36)32-20(27(41)30-16-26(39)40)12-17-4-2-1-3-5-17;/h1-11,20H,12-16H2,(H,28,34)(H,29,35)(H,30,41)(H,31,33)(H,32,36)(H,37,38)(H,39,40);/b11-10-;/t20-;/m0./s1
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| InChIKey |
VQQJXQGTQPHOFR-SIKJREPKSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
599.622
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Polar area
|
220.1
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Complexity
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1242.876421
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xlogp Value
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-0.3827
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Heavy Count
|
42
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Rot Bonds
|
15
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Hbond acc
|
7
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker