Linker Information
General Information of This Linker
| Linker ID |
LIN0ATOHX
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| Linker Name |
CN119630431A-ADC-82-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C68H100N6O23S2
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| Isosmiles |
O=C(NCCCC[C@@H](C(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(O)=O)=O)=O)=O)NC(CCOCCOCCN(C2=O)C(C(SC3=CC=CC=C3)=C2SC4=CC=CC=C4)=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
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| InChI |
InChI=1S/C68H100N6O23S2/c1-84-27-28-88-33-34-90-37-38-92-41-42-94-45-46-96-49-50-97-48-47-95-44-43-93-40-39-91-36-35-89-32-30-85-24-20-59(75)69-22-12-11-19-57(65(80)70-52-61(77)73-58(66(81)71-53-62(78)79)51-54-13-5-2-6-14-54)72-60(76)21-25-86-29-31-87-26-23-74-67(82)63(98-55-15-7-3-8-16-55)64(68(74)83)99-56-17-9-4-10-18-56/h2-10,13-18,57-58H,11-12,19-53H2,1H3,(H,69,75)(H,70,80)(H,71,81)(H,72,76)(H,73,77)(H,78,79)/t57-,58-/m0/s1
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| InChIKey |
UXGBOCHGDYWFFH-YQOHNZFASA-N
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| Pharmaceutical Properties |
Molecule Weight
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1433.701
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Polar area
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349.4
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Complexity
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2547.967867
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xlogp Value
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2.6096
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Heavy Count
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99
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Rot Bonds
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64
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Hbond acc
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24
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker