Linker Information
General Information of This Linker
| Linker ID |
LIN0ARJQU
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|---|---|---|---|---|---|---|
| Linker Name |
C6-VC-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H40N6O6
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| Isosmiles |
CC([C@H](NC(CCCCC(CN)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(C=C1)CO)=O)=O)C
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| InChI |
InChI=1S/C25H40N6O6/c1-16(2)22(31-21(34)8-4-3-6-19(33)14-26)24(36)30-20(7-5-13-28-25(27)37)23(35)29-18-11-9-17(15-32)10-12-18/h9-12,16,20,22,32H,3-8,13-15,26H2,1-2H3,(H,29,35)(H,30,36)(H,31,34)(H3,27,28,37)/t20-,22-/m0/s1
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| InChIKey |
JFAADFCDILTMKO-UNMCSNQZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
520.631
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Polar area
|
205.74
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Complexity
|
859.8043156
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xlogp Value
|
0.2797
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Heavy Count
|
37
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Rot Bonds
|
17
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Hbond acc
|
7
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker