Linker Information
General Information of This Linker
| Linker ID |
LIN0ALSDE
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| Linker Name |
C12-1 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H40N6O10
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| Isosmiles |
C[C@@H](OCNC(CNC(O)[C@@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)C(O)=O
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| InChI |
InChI=1S/C29H40N6O10/c1-19(29(43)44)45-18-33-24(38)16-32-28(42)21(14-20-8-4-2-5-9-20)34-25(39)17-31-23(37)15-30-22(36)10-6-3-7-13-35-26(40)11-12-27(35)41/h2,4-5,8-9,11-12,19,21,28,32,42H,3,6-7,10,13-18H2,1H3,(H,30,36)(H,31,37)(H,33,38)(H,34,39)(H,43,44)/t19-,21+,28?/m1/s1
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| InChIKey |
GZTMIYONCTXDLL-CVEZQOAESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
632.671
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Polar area
|
232.57
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Complexity
|
1149.649982
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xlogp Value
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-2.0969
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Heavy Count
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45
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Rot Bonds
|
21
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Hbond acc
|
10
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker