Linker Information
General Information of This Linker
| Linker ID |
LIN0AKTWQ
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
DBCO-C4-PEG3-VC-PABC
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C47H60N6O10
|
|||||
| Isosmiles |
CC(C)[C@H](NC(CCOCCOCCOCCNC(CCC(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)=O)=O)=O)C(N[C@H](C(NC4=CC=C(CO)C=C4)=O)CCCCC(N)=O)=O
|
|||||
| InChI |
InChI=1S/C47H60N6O10/c1-33(2)45(47(60)51-39(12-6-8-14-41(48)55)46(59)50-38-19-15-34(32-54)16-20-38)52-43(57)23-25-61-27-29-63-30-28-62-26-24-49-42(56)21-22-44(58)53-31-37-11-4-3-9-35(37)17-18-36-10-5-7-13-40(36)53/h3-5,7,9-11,13,15-16,19-20,33,39,45,54H,6,8,12,14,21-32H2,1-2H3,(H2,48,55)(H,49,56)(H,50,59)(H,51,60)(H,52,57)/t39-,45-/m0/s1
|
|||||
| InChIKey |
JGPSWVDFORVQJO-FMZWIXTRSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
869.029
|
Polar area
|
227.72
|
||
|
Complexity
|
1980.611113
|
xlogp Value
|
3.0716
|
|||
|
Heavy Count
|
63
|
Rot Bonds
|
27
|
|||
|
Hbond acc
|
10
|
Hbond Donor
|
6
|
|||
Each Antibody-drug Conjugate Related to This Linker