Linker Information
General Information of This Linker
| Linker ID |
LIN0AKDQJ
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| Linker Name |
DBCO-BridgednnAA-PEG-VKG
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C66H102N6O20
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| Isosmiles |
O=C(NCC12CC(C(NCCC(N3CC4=C(C#CC5=C3C=CC=C5)C=CC=C4)=O)=O)(C2)C1)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(O)=O)=O)=O
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| InChI |
InChI=1S/C66H102N6O20/c1-52(2)61(62(76)70-56(63(77)78)12-7-8-19-67)71-59(74)18-22-81-24-26-83-28-30-85-32-34-87-36-38-89-40-42-91-44-46-92-45-43-90-41-39-88-37-35-86-33-31-84-29-27-82-25-23-80-21-17-58(73)69-51-65-48-66(49-65,50-65)64(79)68-20-16-60(75)72-47-55-11-4-3-9-53(55)14-15-54-10-5-6-13-57(54)72/h3-6,9-11,13,52,56,61H,7-8,12,16-51,67H2,1-2H3,(H,68,79)(H,69,73)(H,70,76)(H,71,74)(H,77,78)/t56-,61-,65?,66?/m0/s1
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| InChIKey |
MONQNJRWNXCTQW-YHCROYRDSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1299.564
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Polar area
|
320.02
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Complexity
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2396.376855
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xlogp Value
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2.561
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Heavy Count
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92
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Rot Bonds
|
57
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Hbond acc
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20
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Hbond Donor
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6
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Each Antibody-drug Conjugate Related to This Linker