Linker Information
General Information of This Linker
| Linker ID |
LIN0AHZNV
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| Linker Name |
TW202506738A-C-118-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H55N8O16P
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| Isosmiles |
CC1=CC=C(NC([C@@H](NC(CNC(CNC(CNP(NCCN2C(C=CC2=O)=O)(NCCOCCOCOCOCOCOCOCOCOC)=O)=O)=O)=O)C)=O)C=C1
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| InChI |
InChI=1S/C34H55N8O16P/c1-26-4-6-28(7-5-26)41-34(48)27(2)40-31(45)17-36-29(43)16-35-30(44)18-39-59(49,37-10-12-42-32(46)8-9-33(42)47)38-11-13-51-14-15-52-20-54-22-56-24-58-25-57-23-55-21-53-19-50-3/h4-9,27H,10-25H2,1-3H3,(H,35,44)(H,36,43)(H,40,45)(H,41,48)(H3,37,38,39,49)/t27-,59?/m0/s1
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| InChIKey |
JXTHPGXHDIACPE-CXWBDQILSA-N
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| Pharmaceutical Properties |
Molecule Weight
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862.828
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Polar area
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290.01
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Complexity
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1418.872652
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xlogp Value
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-2.04578
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Heavy Count
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59
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Rot Bonds
|
35
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Hbond acc
|
16
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker